Oculodentodigital dysplasia is a condition that affects many parts of the body, including the eyes, teeth, and fingers.
The most common features of oculodentodigital dysplasia affect the eyes, teeth, and fingers and toes. People affected by this condition commonly have small eyes that may be slanted and widely spaced. These individuals may also have glaucoma, or one or both eyes may turn inwards. These eye problems may cause affected individuals to have vision loss. Tooth abnormalities include having small or missing teeth and weak enamel leading to multiple cavities. Finger and toe abnormalities may include having bony growths in the hands or webbing of the skin between the fourth and fifth fingers or toes.
It is believed to be caused by a mutation in the gene GJA1.