Osteogenesis Imperfecta

Osteogenesis Imperfecta


Osteogenesis imperfecta, also known as brittle bone disease, is a group of genetic disorders that mainly affect the bones. It results in bones that break easily.


Bone fractures with no obvious cause.


Osteogenesis imperfecta is a genetic disorder that causes increased bone fractures and collagen defects. The main causes for developing the disorder are a result of mutations in the COL1A1 and COL1A2 genes.



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Last Updated on 14 May 2021